Welcome to LookChem.com Sign In|Join Free

CAS

  • or

580-16-5

Post Buying Request

580-16-5 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

580-16-5 Usage

Description

6-Hydroxyquinoline, also known as 6-quinolol, is a white to light yellow crystal powder with the chemical formula C9H7NO. It is a monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 6. 6-Hydroxyquinoline is an ideal photoacid system for exploring excited-state proton transfer (ESPT) reactions, making it a subject of interest in various research fields.

Uses

Used in Chemical Synthesis:
6-Hydroxyquinoline is used as a key intermediate in the synthesis of various organic compounds, particularly 2,6-substituted-benzo[d]thiazole analogs and 2,4-substituted-benzo[d]thiazole analogs. These analogs have potential applications in pharmaceuticals, agrochemicals, and other industries due to their unique chemical properties and biological activities.
Used in Photochemistry Research:
As an ideal photoacid system, 6-Hydroxyquinoline is used in the study of excited-state proton transfer (ESPT) reactions. Researchers utilize this compound to explore the excited-state proton transfer and geminate recombination processes, which are essential for understanding the behavior of various photochemical systems. This knowledge can be applied to develop new materials and technologies in areas such as solar energy conversion, sensors, and advanced imaging techniques.
Used in Pharmaceutical Industry:
6-Hydroxyquinoline and its derivatives have potential applications in the pharmaceutical industry due to their unique chemical properties. They can be used as building blocks for the development of new drugs with specific therapeutic targets. Additionally, their ability to participate in ESPT reactions makes them valuable in the design of drug delivery systems that can release active ingredients in a controlled manner upon exposure to light.
Used in Material Science:
The photochemical properties of 6-Hydroxyquinoline make it a promising candidate for the development of new materials with applications in optoelectronics, photovoltaics, and light-emitting devices. By understanding and exploiting the ESPT reactions in this compound, researchers can design materials with tailored properties for specific applications, such as light-harvesting systems or light-responsive switches.

Check Digit Verification of cas no

The CAS Registry Mumber 580-16-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,8 and 0 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 580-16:
(5*5)+(4*8)+(3*0)+(2*1)+(1*6)=65
65 % 10 = 5
So 580-16-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO/c11-8-3-4-9-7(6-8)2-1-5-10-9/h1-6,11H

580-16-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Aldrich

  • (304484)  6-Hydroxyquinoline  95%

  • 580-16-5

  • 304484-5G

  • 624.78CNY

  • Detail
  • Aldrich

  • (304484)  6-Hydroxyquinoline  95%

  • 580-16-5

  • 304484-25G

  • 2,104.83CNY

  • Detail

580-16-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name quinolin-6-ol

1.2 Other means of identification

Product number -
Other names 6-Quinolinol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:580-16-5 SDS

580-16-5Relevant articles and documents

Design, synthesis and biological evaluation of novel quinoline-based carboxylic hydrazides as anti-tubercular agents

Chander, Subhash,Ashok, Penta,Cappoen, Davie,Cos, Paul,Murugesan, Sankaranarayanan

, p. 585 - 591 (2016)

In this study, seventeen novel quinoline-based carboxylic hydrazides were designed as potential anti-tubercular agents using molecular hybridization approach and evaluated in-silico for drug-likeness behavior. The compounds were synthesized, purified, and characterized using spectral techniques (like FTIR, 1H NMR, and Mass). The in-vitro anti-tubercular activity (against Mycobacterium tuberculosisH37Ra) and cytotoxicity against human lung fibroblast cells were studied. Among the tested hydrazides, four compounds (6h, 6j, 6l, and 6m) exhibited significant anti-tubercular activity with MIC values below 20?μg/mL. The two most potent compounds of the series, 6j and 6m exhibited MIC values 7.70 and 7.13?μg/mL, respectively, against M.?tuberculosis with selectivity index >26. Structure–activity relationship studies were performed for the tested compounds in order to explore the effect of substitution pattern on the anti-tubercular activity of the synthesized compounds.

Monomeric vanadium oxide: A very efficient species for promoting aerobic oxidative dehydrogenation of N-heterocycles

Xie, Zhenbing,Chen, Bingfeng,Zheng, Lirong,Peng, Fangfang,Liu, Huizhen,Han, Buxing

, p. 431 - 437 (2021/01/11)

Monomeric active species are very interesting in heterogeneous catalysis. In this work, we proposed a method to prepare VOx-NbOy@C catalysts, which involve the one-pot hydrothermal synthesis of inorganic/organic hybrid materials containing V/Nb followed by thermal treatment under a reducing atmosphere. The prepared catalysts were characterized using different techniques, such as high-angle annular dark-field scanning transmission electron microscopy and X-ray absorption fine structure spectroscopy. It was shown that monomeric VOx species were dispersed homogeneously in the catalysts. The VOx-NbOy@C catalysts displayed high performance in the aerobic oxidative dehydrogenation of N-heterocycles to aromatic heterocycles. It was demonstrated that the selectivity of reaction over the catalyst with a very small amount of V (0.07 wt%) was much higher than that over the NbOy@C, and the catalyst also exhibited excellent stability in the reaction. The detailed study indicated that monomeric VO2 species were the most effective for promoting the reaction. This journal is

Radical-anion coupling through reagent design: hydroxylation of aryl halides

Chechik, Victor,Greener, Andrew J.,James, Michael J.,Oca?a, Ivan,Owens-Ward, Will,Smith, George,Ubysz, Patrycja,Whitwood, Adrian C.

, p. 14641 - 14646 (2021/11/17)

The design and development of an oxime-based hydroxylation reagent, which can chemoselectively convert aryl halides (X = F, Cl, Br, I) into phenols under operationally simple, transition-metal-free conditions is described. Key to the success of this approach was the identification of a reducing oxime anion which can interact and couple with open-shell aryl radicals. Experimental and computational studies support the proposed radical-nucleophilic substitution chain mechanism.

Reversible aerobic oxidative dehydrogenation/hydrogenation of N-heterocycles over AlN supported redox cobalt catalysts

He, Zhen-Hong,Sun, Yong-Chang,Wang, Kuan,Wang, Zhong-Yu,Guo, Pan-Pan,Jiang, Chong-Shan,Yao, Man-Qing,Li, Zhu-Hui,Liu, Zhao-Tie

, (2020/09/16)

N-heterocycles with quinoline and tetrahydroquinoline structures are highly important in pharmaceutical and chemical industries, and their highly efficient mutual transformations are vital but still challenging. In the present work, AlN supported redox cobalt catalysts (Co3O4/AlN and Co/AlN) were prepared, which could achieve the reversible aerobic oxidative dehydrogenation/hydrogenation of N-heterocycles with good performances. The catalytic performances were stem from the strong interaction between Co species with AlN support, which were confirmed by the characterizations of Raman, XPS, UV–vis DRS, and H2-TPR etc. Both of the catalysts showed good stabilities and reusabilities for the titled reactions. Besides, the gram-scale experiments achieved with good yields to corresponding products, revealing the present protocol possesses great potential applications in industry. The strategy of using redox Co-based catalyst not only provides a potential catalyst for the reversible hydrogenation/oxidative dehydrogenation reactions but also replenishes methods for constructing of other redox catalyst, especially with AlN as a carrier.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 580-16-5