108827-55-0Relevant articles and documents
A MESO SPECIFIC REACTION
Thottathil, John K.,Przybyla, Claire,Malley, Mary,Gougoutas, J. Z.
, p. 1533 - 1536 (2007/10/02)
Acid-catalyzed condensation of optically pure 5-(hydroxymethyl)-2-pyrrolidinone, 2, with benzaldehyde gives only a monomeric optically active oxazolidine, 3, while under the same conditions, racemic 2 gives only a meso centrosymmetric compound 4 - a dimer of racemic 3.This meso specific reaction serves as a highly efficient method for increasing the optical purity of the generally useful chiral building blocks 2 and 3.
