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108840-66-0

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108840-66-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 108840-66-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,8,4 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 108840-66:
(8*1)+(7*0)+(6*8)+(5*8)+(4*4)+(3*0)+(2*6)+(1*6)=130
130 % 10 = 0
So 108840-66-0 is a valid CAS Registry Number.

108840-66-0Downstream Products

108840-66-0Relevant articles and documents

Dynamic Kinetic Resolution of I-Substituted Cyclic β-Ketoesters via Asymmetric Hydrogenation: Constructing Chiral Cyclic β-Hydroxyesters with Three Contiguous Stereocenters

Yang, Dan,Wu, Xiong,Zheng, Xiao-Jie,Xie, Jian-Hua,Zhou, Qi-Lin

, p. 5153 - 5157 (2021)

An efficient asymmetric hydrogenation of racemic I-substituted cyclic β-ketoesters via dynamic kinetic resolution to provide chiral cyclic β-hydroxy esters with three contiguous stereocenters is reported. Using a chiral spiro iridium catalyst (R)-5 (Ir-SpiroSAP), a series of racemic I-Aryl/alkyl substituted cyclic β-ketoesters were hydrogenated to the corresponding chiral cyclic β-hydroxy esters in high yields (84-97%) with good to excellent enantioselectivities (69->99% ee) and cis,cis-selectivities (up to >99:1).

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