1088539-80-3Relevant academic research and scientific papers
Regulation of human carbonic anhydrase I (hCAI) activity by using a photochromic inhibitor
Vomasta, Daniel,Hoegner, Christina,Branda, Neil R.,Koenig, Burkhard
supporting information; experimental part, p. 7644 - 7647 (2009/04/11)
Photoswitchable: The activity of a dithienylethene-based human carbonic anhydrase inhibitor (hCAI) can be regulated using light. Converting the flexible, ring-open isomer of the photoswitch into the rigid, ring-closed isomer using UV light reduces the inhibition and increases the activity of hCAI by 50-fold. The inhibitor can be turned back on by using visible light, which has many advantages in biological applications.
