108868-40-2

Upstream product

• 108868-37-7 4-bromo-3-(2-acetamido-2-carbomethoxyethen-1-yl)-1-tosylindole 
• 90481-83-7 4-bromo-3-iodo-1-tosyl-1H-indole 
• 35356-70-8 Methyl 2-acetamidoacrylate 

Downstream Products

• 108894-42-4 3-(2-acetamido-2-carbomethoxyethyl)-4-(3-hydroxy-3-methyl-1-buten-1-yl)-1-tosylindole 
• 108894-43-5 2-Acetylamino-3-[4-((E)-3-methyl-buta-1,3-dienyl)-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Palladium-Catalyzed Reactions in the Synthesis of 3- and 4-Substituted Indoles. 2. Total Synthesis of the N-Acetyl Methyl Ester of (+/-)-Claviciptic Acids

The N-acetyl methyl esters of the (+/-)-claviciptic acids 9 were synthesized in 12 steps in overall 18percent yield from commercially available 2-bromo-6-nitrotoluene.The synthesis involved, as key steps, Pd(II)-catalyzed formation of the indole and seven-membered nitrogen-containing C-ring and Pd(0)-catalyzed introduction of both C-ring side-chain precursors.