1088979-79-6Relevant academic research and scientific papers
Sunlight-Driven Forging of Amide/Ester Bonds from Three Independent Components: An Approach to Carbamates
Zhao, Yating,Huang, Binbin,Yang, Chao,Chen, Qingqing,Xia, Wujiong
, p. 5572 - 5575 (2016/11/17)
A photoredox catalytic route to carbamates enabled by visible irradiation (or simply sunlight) has been developed. This process leads to a novel approach to the construction of heterocyclic rings wherein the amide or ester motifs of carbamates were assembled from three isolated components. Large-scale experiments were realized by employing continuous flow techniques, and reuse of photocatalyst demonstrated the green and sustainable aspects of this method.
Visible light photooxidative cyclization of amino alcohols to 1,3-oxazines
Mathis, Cheryl L.,Gist, Brandi M.,Frederickson, Conerd K.,Midkiff, Katie M.,Marvin, Christopher C.
supporting information, p. 2101 - 2104 (2013/04/24)
1,3-Amino alcohols were prepared to examine how structure affects the oxidation of tertiary amines in visible light photocatalysis. These substrates were cyclized to produce oxazines following the photooxidative formation of iminium ions using catalytic Ru(bpy)3Cl2. Amino alcohol derivatives of tetrahydroisoquinoline, tetrahydroquinoline, pyrrolidine, and Δ3-piperidine all were found to be viable substrates. In the case of the unsaturated piperidines, cyclization is accompanied by addition of methanol across the alkene; most likely occurring via a conjugate addition to an intermediate α,β-unsaturated iminium ion prior to oxazine formation.
New gas-phase cascade reactions of stabilized phosphorus ylides leading to ring-fused indoles and to quinolines
Aitken, R. Alan,Murray, Lorna
supporting information; experimental part, p. 9781 - 9783 (2009/04/06)
(Chemical Equation Presented) Gas-phase cyclization processes of stabilized phosphorus ylides bearing a suitably substituted 2-aminophenyl group lead efficiently either to 3-substituted quinolines or benzo[c]-carbazole and heterocyclic-fused analogues depending on the substituents present.
