108907-43-3

Upstream product

• 773859-54-4 (+)-(2R,3S)-trans-5,7-bis(benzyloxy)-2-(4-benzyloxyphenyl)chroman-3-ol 
• 773859-58-8 (-)-(2R,3R)-cis-5,7-bis(benzyloxy)-2-(4-benzyloxyphenyl)chroman-3-ol 
• 773859-52-2 (E)-3-[2,4-bis(benzyloxy)-6-hydroxyphenyl]-1-(4-benzyloxyphenyl)propene 
• 1486-47-1 3,4,5-tris(benzyloxy)benzoyl chloride 
• 1486-48-2 3,4,5-tribenzyloxybenzoic acid 
• 63604-98-8 1,3-dibenzylphloroglucinol 
• 773859-55-5 (+)-(2R,3S)-trans-5,7-bis(benzyloxy)-2-(4-benzyloxyphenyl)chroman-3-yl 3,4,5-tris(benzyloxy)benzoate 
• 773859-57-7 (+)-(2R)-5,7-bis(benzyloxy)-2-(4-benzyloxyphenyl)chroman-3-one 
• 773859-60-2 (-)-(2R,3R)-cis-5,7-bis(benzyloxy)-2-(4-benzyloxyphenyl)chroman-3-yl 3,4,5-tris(benzyloxy)benzoate 
• 84184-52-1 (E)-3-(4-(benzyloxy)phenyl)prop-2-en-1-ol 

Downstream Products

• 490-61-9 (-)-epiafzelechin 

Relevant academic research and scientific papers

General synthesis of epi-series catechins and their 3-gallates: Reverse polarity strategy

A general synthetic route to the epi-series catechins was developed based on the reverse polarity strategy. Aromatic nucleophilic substitution reaction followed by the sulfinyl-metal exchange and cyclization enabled stereo-controlled access to various members of epi-series catechins and their 3-gallates.

Enantioselective synthesis of afzelechin and epiafzelechin

The flavonoids afzelechin and epiafzelechin as well as their gallate esters were synthesized enantioselectively via Sharpless hydroxylation followed by regioselective cyclization. Graphical Abstract

PROANTHOCYANIDINS OF Rhodiola semenovii

The structures of two compounds previously isolated from Rhodiola semenovii, rhodokhinoside (I) and rhodikhim (II), have been established.