1089280-09-0

Basic information

• Product Name: (3R)-5-oxo-N,4-bis(phenylmethyl)-3-morpholinecarboxamide
• Synonyms: (3R)-5-oxo-N,4-bis(phenylmethyl)-3-morpholinecarboxamide
• CAS NO: 1089280-09-0
• Molecular Weight: 324.379
• Mol File: 1089280-09-0.mol

Chemical Properties

• CAS DataBase Reference: (3R)-5-oxo-N,4-bis(phenylmethyl)-3-morpholinecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)-5-oxo-N,4-bis(phenylmethyl)-3-morpholinecarboxamide(1089280-09-0)
• EPA Substance Registry System: (3R)-5-oxo-N,4-bis(phenylmethyl)-3-morpholinecarboxamide(1089280-09-0)

Safety Data

• Hazardous Substances Data: 1089280-09-0(Hazardous Substances Data)

Upstream product

• 106910-77-4 N-(phenylmethyl)-D-serine 
• 100-52-7 benzaldehyde 
• 106973-36-8 (3R)-5-oxo-4-(phenylmethyl)-3-morpholinecarboxylic acid 
• 100-46-9 benzylamine 

Downstream Products

• 1089280-12-5 ethyl oxo((phenylmethyl){[(3S)-4-(phenylmethyl)-3-morpholinyl]methyl}amino)acetate 
• 1089280-11-4 (9aS)-8-(phenylmethyl)hexahydropyrazino[2,1-c][1,4]oxazine-6,7-dione 
• 1089280-13-6 (9aS)-8-(phenylmethyl)octahydropyrazino[2,1-c][1,4]oxazine 
• 1126432-04-9 (9aS)-1,3,4,6,7,8,9,9a-octahydropyrazino[2,1-c][1,4]oxazine dihydrochloride 
• 1152110-20-7 [(2R)-2-(cyclopentylmethyl)-3-(2-{5-fluoro-6-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-methyl-4-pyrimidinyl}hydrazino)-3-oxopropyl][(phenylmethyl)oxy]formamide 
• 1152107-25-9 GSK1322322 
• 1152110-17-2 1-phenyl-N-{[(3S)-4-(phenylmethyl)-3-morpholinyl]methyl}methanamine 

Relevant articles and documents

PEPTIDE DEFORMYLASE INHIBITORS

The present invention relates to {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3- oxopropyl}hydroxyformamide compounds of Formula (I): or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, processes for making and use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity and in treatment methods for bacterial infections

PEPTIDE DEFORMYLASE INHIBITORS

The present invention is directed to certain {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide derivatives, compositions containing them, the use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity, and in the treatment of bacterial infections. Specifically, the invention is directed to compounds of formula (I), wherein R1, R2 and R3 are defined herein and to pharmaceutically acceptable salts thereof. The compounds of this invention are bacterial peptide deformylase inhibitors and can be useful in the treatment of bacterial infections.

Imidazopyridine Kinase Inhibitors

The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.