108944-70-3Relevant academic research and scientific papers
O-1-(1,3-butadienyl) carbamates as diels-alder dienes: Stereospecific synthesis of (±)-Hernandulcin and congeners
De Cusati, Paul F.,Olofson
, p. 1409 - 1412 (2007/10/02)
The TiCl4-catalyzed addition of the title reactants to vinyl ketones regio- and stereospecifically yields cis-disubs, cyclohexenes which add RMgX stereospecifically to the ketone. A final product in this sequence is the intensely sweet sesquiterpene, hernandulcin.
Synthesis of (+/-)-Hernandulcin by an Intramolecular Nitrile Oxide Cycloaddition Route from Farnesol
Zheng, Guo-Chi,Kakisawa, Hiroshi
, p. 602 - 604 (2007/10/02)
An intramolecular addition reaction of the nitrile oxide derived from (2Z,6E)-farnesal oxime afforded an isoxazoline derivative, which was converted into hernandulcin, a sweet sesquiterpene of Verbenaceae plant.
