108948-29-4

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 108948-27-2 3-(2,2-diethoxyethyl)-4-(3-hydroxy-3-methyl-1-buten-1-yl)-1-tosylindole 
• 108948-24-9 4-bromo-3-(2,2-diethoxyethyl)-1-tosylindole 
• 108948-23-8 4-bromo-3-(2-ethoxyethen-1-yl)-1-tosylindole 
• 90481-83-7 4-bromo-3-iodo-1-tosyl-1H-indole 

Downstream Products

• 108948-30-7 2,3-dicarbomethoxy-1,5-ditosyl-5,6-dihydro-6-(2-methyl-1-propenyl)azepino<5,4,3-cd>indole 

Relevant academic research and scientific papers

Palladium Catalyzed Reactions in the Synthesis of 3- and 4-Substituted Indoles. 3. Total Synthesis of (+/-)-Aurantioclavine

(+/-)-Aurantioclavine (9) was synthesized in overall 23percent yield and 13 steps from comercially available starting materials.The synthesis involved palladium(II)-catalyzed indole ring formation, nickel(0)/zirconium(IV)-assisted introduction of one side chain, palladium(0)-catalyzed introduction of the other side chain, acid-catalyzed cyclization to form the seven-membered ring, and photolytic reductive detosylation to produce 9.