1089665-72-4Relevant academic research and scientific papers
Modularly designed organocatalytic assemblies for direct nitro-Michael addition reactions
Mandal, Tanmay,Zhao, Cong-Gui
, p. 7714 - 7717 (2008)
It's so simple! Organocatalysts formed through the self-assembly of simple α-amino acids and alkaloid thiourea derivatives (see scheme) are used as highly efficient catalysts for the direct nitro-Michael addition of ketones and nitroalkenes, affording excellent ee values up to 99%. Enantioselectivity may be tuned by changing components of the self-assembled catalyst.
