108975-51-5

Upstream product

• 109-65-9 1-bromo-butane 
• 68-34-8 phenyl toluenesulfonamide 
• 109-69-3 n-Butyl chloride 
• 613-29-6 N-Dibutylaniline 
• 98-59-9 p-toluenesulfonyl chloride 
• 778-28-9 butyl para-toluenesulfonate 
• 1907-65-9 N-butyl-4-toluenesulfonamide 
• 66003-76-7 Diphenyliodonium triflate 

Downstream Products

• 1126-78-9 N-(n-butyl)aniline 

Relevant academic research and scientific papers

Synthesis of sulfonamides: Via copper-catalyzed oxidative C-N bond cleavage of tertiary amines

A copper-catalyzed coupling reaction of sulfonyl chlorides with tertiary amines via the oxidative C-N bond cleavage of tertiary amines was developed. Sulfonamides were synthesized using this strategy in moderate to good yields. The reaction was applicable to various tertiary amines, as well as sulfonyl chlorides.

Copper-catalyzed direct N-arylation of N-arylsulfonamides using diaryliodonium salts in water

An efficient copper-catalyzed N-arylation of N-arylsulfonamides with diaryliodonium salts is reported. The reaction employs diaryliodonium salts and N-arylsulfonamides in water at room temperature, giving the products in moderate to excellent yields.