109004-06-0

Upstream product

• 109004-02-6 (2S,3S)-2-Hydroxy-3-((1aR,3aR,3bS,5aS,8aS,8bR,10R,10aR)-10-methoxy-3a,5a-dimethyl-1,1a,2,3,3a,3b,4,5,5a,8,8a,8b,9,10-tetradecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-butyric acid methyl ester 
• 73668-91-4 (17E)-6β-methoxy-3α,5-cyclo-5α-pregn-17(20)-en-16α-ol 
• 109004-00-4 [(1aR,3aR,3bS,5aS,7R,8aS,8bR,10R,10aR)-6-Eth-(E)-ylidene-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-7-yloxy]-acetic acid 
• 100-39-0 benzyl bromide 
• 109004-04-8 (2S,3S)-2-Benzyloxy-3-((1aR,3aR,3bS,5aS,6R,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-butyric acid methyl ester 

Relevant academic research and scientific papers

APPLICATION OF WITTIG AND CLAISEN REARRANGEMENTS IN STEROID SIDE CHAIN SYNTHESIS. A HIGHLY STEREOCONTROLLED ENTRY TO EITHER (22S)- OR (22R)-HYDROXY-23-CARBOXYLIC ACID

An efficient approach to either (22S)- or (22R)-hydroxy-23-carboxylic acid side chain is described which relies on the stereochemical transmission via Wittig or Claisen sigmatropic rearrangement, respectively.