109005-10-9

Usage

Uses

Used in Cancer Prevention:
10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole is used as a cancer prevention agent for its potential role in modulating the metabolism of estrogen in the body, which may help reduce the risk of hormone-related cancers.
Used in Antioxidant Applications:
10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole is used as an antioxidant, helping to neutralize harmful free radicals and protect cells from oxidative damage, which may contribute to the prevention of various diseases, including cancer.
Used in Anti-Inflammatory Applications:
10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole is used as an anti-inflammatory agent, potentially reducing inflammation in the body and alleviating symptoms associated with inflammatory conditions.
Used in Immune Modulation:
10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole is used as an immune modulator, potentially enhancing the body's immune response and helping to fight off infections and diseases.
Used in Dietary Supplements:
10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole is used as a dietary supplement, providing potential health benefits such as cancer prevention, antioxidant, anti-inflammatory, and immune-modulating properties.
Used in Pharmaceutical Research:
10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole is used in pharmaceutical research for its potential therapeutic applications in various health conditions, including cancer prevention and treatment, as well as other diseases related to inflammation and immune function.
Used in Nutraceutical Industry:
In the nutraceutical industry, 10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole is used as a functional ingredient in health products, leveraging its anti-cancer, antioxidant, anti-inflammatory, and immune-modulating properties to promote overall health and well-being.
Used in Cosmetics Industry:
In the cosmetics industry, 10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole may be used as an active ingredient in anti-aging and skin health products, due to its antioxidant and anti-inflammatory properties, which can help protect and rejuvenate the skin.
Used in Functional Foods:
10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole can be used in the development of functional foods, where it can provide health benefits beyond basic nutrition, such as cancer prevention and immune support.
Used in Agricultural Products:
In agricultural products, 10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole may be used as a natural pesticide or growth promoter, leveraging its anti-inflammatory and immune-modulating properties to enhance plant health and resistance to diseases.

Upstream product

• 120-72-9 indole 
• 1484-27-1 3-bromoindole 
• 307519-55-7 2,3,7,8,12,13-hexabromo-10,15-dihydro-5H-diindolo[3,2-a:3',2'-c]-carbazole 
• 59-48-3 2-oxoindole 
• 2365-44-8 3-hydrazonoindolin-2-one 
• 25250-89-9 2H-indol-2-one 
• 91-56-5 indole-2,3-dione 

Downstream Products

• 757233-23-1 5,10,15-tris(1-bromo-2-phenylmethyl)-10,15-dihydro-5H-5,10,15-triaza-diindeno[1,2-a;1',2'-c]fluorene 
• 879713-04-9 5,10,15-triphenyl-10,15-dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole 
• 1092536-44-1 5,10,15-tribenzyl-10,15-dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole 

Relevant academic research and scientific papers

A hydrophilic three side-chained triazatruxene as a new strong and selective G-quadruplex ligand

A new hydrosoluble triazatruxene derivative (AZATRUX) is reported to selectively bind to G-quadruplex DNA, as derived by ESI-MS measurements and competition experiments. The Royal Society of Chemistry 2009.

Triazatruxene–Rhodamine-Based Ratiometric Fluorescent Chemosensor for the Sensitive, Rapid Detection of Trivalent Metal Ions: Aluminium (III), Iron (III) and Chromium (III)

We investigated the ability of a novel triazatruxene–rhodamine-based (TAT-ROD) chemosensor to detect the trivalent metal ions aluminium (Al3+), iron (Fe3+) and chromium (Cr3+). Operating via the through-bond energy transfer (TBET) pathway, the chemosensor exhibited low detection limits of 23.0, 25.0 and 170.0 nM for Al3+, Fe3+ and Cr3+, respectively, along with high sensitivity and selectivity during a brief period (15 s). The binding ratio of the chemosensor and trivalent metal ions achieved by Job’s method was 3:1, and when we added ethylenediaminetetraacetic acid (EDTA), the sensing process reversed. Altogether, our TAT-ROD chemosensor marks the first triazatruxene-based colorimetric and fluorometric metal ion sensor reported in the literature.

Tetra-indole core as a dual agent: A hole selective layer that passivates defects in perovskite solar cells

An organic small molecule composed of a tetra-indole core was designed and introduced as a hole selective layer for the fabrication of perovskite solar cells (PSCs). 5,10,15,20-Tetrahydrotriindole[2′,3′:4:2′,3′:5,6:2′,3′:7,8]cycloocta[1,2-b]indole (TTI) when integrated in PSCs, also passivated the defects in perovskite by suppressing the non-radiative recombination as noted from photoluminescence and electrochemical impedance (EIS) measurements and gave improved photovoltaic performances. The device showed a power conversion efficiency of 15.83% when employed as an hole selective layer, however on passivating the interface of perovskite/hole selective layer, the PCE improved significantly to 19.23%. Additionally, the TTI treated device showed improved charge transfer behaviour and long-term stability when stored in the dark under an ambient atmosphere.

Azatruxene-Based, Dumbbell-Shaped, Donor–π-Bridge–Donor Hole-Transporting Materials for Perovskite Solar Cells

Three novel donor–π-bridge–donor (D-π-D) hole-transporting materials (HTMs) featuring triazatruxene electron-donating units bridged by different 3,4-ethylenedioxythiophene (EDOT) π-conjugated linkers have been synthesized, characterized, and implemented in mesoporous perovskite solar cells (PSCs). The optoelectronic properties of the new dumbbell-shaped derivatives (DTTXs) are highly influenced by the chemical structure of the EDOT-based linker. Red-shifted absorption and emission and a stronger donor ability were observed in passing from DTTX-1 to DTTX-2 due to the extended π-conjugation. DTTX-3 featured an intramolecular charge transfer between the external triazatruxene units and the azomethine–EDOT central scaffold, resulting in a more pronounced redshift. The three new derivatives have been tested in combination with the state-of-the-art triple-cation perovskite [(FAPbI3)0.87(MAPbBr3)0.13]0.92[CsPbI3]0.08 in standard mesoporous PSCs. Remarkable power conversion efficiencies of 17.48 percent and 18.30 percent were measured for DTTX-1 and DTTX-2, respectively, close to that measured for the benchmarking HTM spiro-OMeTAD (18.92 percent), under 100 mA cm?2 AM 1.5G solar illumination. PSCs with DTTX-3 reached a PCE value of 12.68 percent, which is attributed to the poorer film formation in comparison to DTTX-1 and DTTX-2. These PCE values are in perfect agreement with the conductivity and hole mobility values determined for the new compounds and spiro-OMeTAD. Steady-state photoluminescence further confirmed the potential of DTTX-1 and DTTX-2 for hole-transport applications as an alternative to spiro-OMeTAD.

Study of a convenient method for the preparation of hydrosoluble fluorescent triazatruxene derivatives

Triazatruxene derivatives find many applications as lipophilic compounds, but few examples of hydrosoluble derivatives have been reported so far. In this paper, we compare different synthetic routes for the preparation of hydrophilic triazatruxene derivatives and define the most versatile pathway. The synthesized compounds are fluorescent not only in organic solvents, as reported for other lipophilic derivatives, but also in water, making them particularly suitable for biological applications.

Cation-π induced lithium-doped conjugated microporous polymer with remarkable hydrogen storage performance

A cation-π induced lithium-doped conjugated microporous polymer, Li+-PTAT, was constructed. It was proved that the point to face cation-π interactions between Li+ and indole can endow the resulting Li+-PTAT with high Li+ content and without agglomeration, which further leads to its encouraging hydrogen storage capacity.

Effects of ethynyl unit and electron acceptors on the performance of triazatruxene-based dye-sensitized solar cells

Metal-free organic dyes JY43-JY46 based on the triazatruxene donor were synthesized for dye-sensitized solar cells (DSSCs), where the effects of ethynyl unit and electron acceptor/anchor were systematically investigated. Compared to dyes JY45 and JY46, JY

Triazatruxene-Based Hole Transporting Materials for Highly Efficient Perovskite Solar Cells

Four center symmetrical star-shaped hole transporting materials (HTMs) comprising planar triazatruxene core and electron-rich methoxy-engineered side arms have been synthesized and successfully employed in (FAPbI3)0.85(MAPbBr3)0.15 perovskite solar cells. These HTMs are obtained from relatively cheap starting materials by adopting facile preparation procedure, without using expensive and complicated purification techniques. Developed compounds have suitable highest occupied molecular orbitals (HOMO) with respect to the valence band level of the perovskite, and time-resolved photoluminescence indicates that hole injection from the valence band of perovskite into the HOMO of triazatruxene-based HTMs is relatively more efficient as compared to that of well-studied spiro-OMeTAD. Remarkable power conversion efficiency over 18% was achieved using 5,10,15-trihexyl-3,8,13-tris(4-methoxyphenyl)-10,15-dihydro-5H-diindolo[3,2-a:3′,2′-c]carbazole (KR131) with compositive perovskite absorber. This result demonstrates triazatruxene-based compounds as a new class of HTM for the fabrication of highly efficient perovskite solar cells.

Solution processed organic light-emitting diodes using a triazatruxene crosslinkable hole transporting material

A cross-linkable triazatruxene that leads to insoluble films upon thermal annealing at temperatures compatible with flexible substrates is presented. The films were used as the hole transporting and electron blocking layer in partially solution processed phosphorescent organic light-emitting diodes, reaching power conversion efficiencies of 24 lm W?1, an almost 50% improvement compared to the same OLEDs without the cross-linkable hole transporting layer.

Octupolar (C3 and S4) Symmetric Cyclized Indole Derivatives: Syntheses, Structures, and NLO Properties

Several cyclized indole derivatives have been synthesized, and their structures been determined. The C3-symmetric single-chiral N-phenyltriindole (Tr-Ph3) crystallized in the P1 space group, and the S4-symmetric saddle-like tetraindo