109023-01-0

Basic information

• Product Name: 2-(2,3,5,6-tetrafluorophenoxy)aniline
• Synonyms: 2-(2,3,5,6-tetrafluorophenoxy)aniline
• CAS NO: 109023-01-0
• Molecular Weight: 257.187
• Mol File: 109023-01-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2,3,5,6-tetrafluorophenoxy)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,3,5,6-tetrafluorophenoxy)aniline(109023-01-0)
• EPA Substance Registry System: 2-(2,3,5,6-tetrafluorophenoxy)aniline(109023-01-0)

Safety Data

• Hazardous Substances Data: 109023-01-0(Hazardous Substances Data)

Upstream product

• 363-72-4 Pentafluorobenzene 
• 95-55-6 2-amino-phenol 

Downstream Products

• 109002-38-2 N-[2-(2,3,5,6-Tetrafluoro-phenoxy)-phenyl]-acetamide 

Relevant articles and documents

Selective C4-F bond cleavage/C-O bond formation of polyfluoroarenes with phenols and benzyl alcohols

A facile and efficient SNAr method for the synthesis of unsymmetrical polyfluoroaryl ethers via selective C4-F bond cleavage of pentafluorobenzene is reported. The reaction could proceed smoothly without the requirement of additional metals or ligands, and afford a series of the corresponding products in good to high yields. A wide variety of substituted phenols and alcohols provided 1,2,4,5-tetrafluoropheny ether derivatives in regioselective manner.