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1090478-08-2

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1090478-08-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1090478-08-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,0,4,7 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1090478-08:
(9*1)+(8*0)+(7*9)+(6*0)+(5*4)+(4*7)+(3*8)+(2*0)+(1*8)=152
152 % 10 = 2
So 1090478-08-2 is a valid CAS Registry Number.

1090478-08-2Downstream Products

1090478-08-2Relevant articles and documents

Modulation of 11β-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazoles

Webster, Scott P.,Binnie, Margaret,McConnell, Kirsty M.M.,Sooy, Karen,Ward, Peter,Greaney, Michael F.,Vinter, Andy,Pallin, T. David,Dyke, Hazel J.,Gill, Matthew I.A.,Warner, Ines,Seckl, Jonathan R.,Walker, Brian R.

, p. 3265 - 3271 (2010)

Inhibitors of 11β-hydroxysteroid dehydrogenase (11β-HSD1) show promise as drugs to treat metabolic disease and CNS disorders such as cognitive impairment. A series of 1,5-substituted 1H-tetrazole 11β-HSD1 inhibitors has been discovered and chemically modified. Compounds are selective for 11β-HSD1 over 11β-HSD2 and possess good cellular potency in human and murine 11β-HSD1 assays. A range of in vitro stabilities are observed in human liver microsome assays.

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