109057-27-4Relevant academic research and scientific papers
Visual chiral recognition of mandelic acid and α-amino acid derivatives by enantioselective gel formation and precipitation
Tripathi, Anamica,Kumar, Anjul,Pandey, Pramod S.
supporting information, p. 5745 - 5748 (2012/11/06)
Novel chiral receptors based on l-phenylalanine and l-valine have been synthesized and their chiral recognition properties toward mandelic acid and N-tosyl α-amino acids are studied. The phenylalanine-based receptor undergoes enantioselective gel formation with R-mandelic acid and N-tosyl-d-valine, whereas the valine-linked receptor in their presence results in the formation of precipitates.
Addressing the stability of C-capped dipeptide efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa
Renau, Thomas E,Leger, Roger,Flamme, Eric M,She, Miles W,Gannon, Carla L,Mathias, Kristina M,Lomovskaya, Olga,Chamberland, Suzanne,Lee, Ving J,Ohta, Toshiharu,Nakayama, Kiyoshi,Ishida, Yohei
, p. 663 - 667 (2007/10/03)
Synthetic optimization of a biologically labile class of dipeptides that function as efflux pump inhibitors to potentiate the antibacterial agent levofloxacin in Pseudomonas aeruginosa has led to the discovery of a related series of compounds that are completely stable in a variety of biological matrices. Other than the stability profile, the in vitro profile of the new series is essentially identical to that observed with the original one. A prototypical compound from the new series demonstrates potentiation in an in vivo model of infection.
PAPAIN-CATALYZED SYNTHESIS OF 2-NAPHTHYLAMIDES OF N-ACYLAMINO ACIDS AND DIPEPTIDES
Cerovsky, Vaclav,Saks, Tatana,Jost, Karel
, p. 2309 - 2316 (2007/10/02)
2-Naphthylamides of several N-acylamino acids were prepared by papain-catalyzed condensation reaction in acidic medium.Under the same conditions, papain catalyzed the synthesis of peptide bond between benzyloxycarbonylglycine and phenylalanine 2-naphthyla
SYNTHESIS OF GLYCYL-L-PHENYLALANINE 2-NAPHTHYLAMIDE HYDROCHLORIDE - CATHEPSIN S SUBSTRATE
Muratov, V. B.,Kharchevnikov, A. P.
, p. 1554 - 1556 (2007/10/02)
The synthesis of glycyl-L-phenylalanine 2-naphthylamide hydrochloride with an optical purity of not less than 97percent is described.This compound was obtained by the condensation of tert-butyloxycarbonylglycine with L-phenylalanine 2-naphthylamide triflu
