109072-22-2Relevant academic research and scientific papers
SYNTHETIC CONNECTIONS TO THE AROMATIC DIRECTED METALATION REACTION. A MODIFIED von NIEMENTOWSKI QUINOLINE SYNTHESIS FROM ANTHRANILAMIDES
Chong, R.J.,Siddiqui, M.A.,Snieckus, V.
, p. 5323 - 5326 (2007/10/02)
Anthranilamides 1, A = NR2 derived from benzamides by directed ortho metalationamination, are converted into the corresponding imines 4 which upon treatment with LDA lead to substituted 4-quinolones 5 thus providing a general new quinoline synthesis (Tabl
