109090-35-9Relevant articles and documents
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Cohen,S.G.,Green,B.
, p. 6824 - 6829 (1969)
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SYNTHESIS OF 1,2-DIAMINO-1,2-DIPHENYLBUTANE BY TITANIUM INDUCED REACTION OF AMMONIA WITH ACETOPHENONE
Volckaerts, E.,Geise, H. J.,Daelmans, F.,Claereboudt, J.
, p. 497 - 502 (2007/10/02)
Reaction at room temperature of gaseous ammonia with acetophenone under the influence of low-valent titanium - prepared from TiCl3 : LiAlH4 in the molar ratio 2 : 1 - leads to formation of 2,3-diamino-2,3-diphenylbutane in a synthetically useful yield (58 percent).It is essential to simultaneously add NH3 and ketone keeping their ratio 1:1 until the ratio Ti : NH3 : ketone = 1:1:1 is reached.Mass spectral characteristics and other spectroscopic properties of the new compound and of some side compounds are discussed.A plausible mechanism of the aminative reductive ketone coupling is given.