Welcome to LookChem.com Sign In|Join Free
  • or
Estr-5(10)-ene-3,6,17-trione, also known as 6-ketoestradiol, is a naturally occurring steroidal compound derived from the metabolism of estradiol, a primary female sex hormone. estr-5(10)-ene-3,6,17-trione is characterized by its unique structure, featuring a 5(10) double bond, a 3-keto group, and a 17-keto group. It plays a significant role in the endocrine system and has been implicated in various physiological processes, including bone metabolism and the cardiovascular system. Research has also suggested that 6-ketoestradiol may have potential therapeutic applications, particularly in the context of hormone-related disorders. However, further studies are needed to fully understand its mechanisms of action and potential clinical uses.

1091-89-0

Post Buying Request

1091-89-0 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1091-89-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1091-89-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,9 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1091-89:
(6*1)+(5*0)+(4*9)+(3*1)+(2*8)+(1*9)=70
70 % 10 = 0
So 1091-89-0 is a valid CAS Registry Number.

1091-89-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name estr-5(10)-ene-3,6,17-trione

1.2 Other means of identification

Product number -
Other names 5(10)-Estrene-3,6,17-trione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1091-89-0 SDS

1091-89-0Downstream Products

1091-89-0Relevant academic research and scientific papers

C(10)-C(19) bond cleavage reaction of 19-oxygenated androst-4-ene-3,6-dione steroids under various conditions

Nagaoka, Masao,Numazawa, Mitsuteru

, p. 983 - 985 (2004)

C(10)-C(19) bond cleavage reaction of 19-hydroxy- and 19-oxoandrost-4-ene- 3,6,17-triones (5, 6) was explored under various conditions. Treatment of steroids 5 and 6 with KOH in MeOH gave the A-ring aromatized product 6-oxoestrone (11) in a fair yield, respectively, in contrast, the treatment with a weak base yielded 4-methyl steroid 17 (20%) in the case of 19-alcohol 5 or 19-nor- Δ5(10)-steroid 9 (12-67%) along with compound 11 (6-27%) in the case of 19-aldehyde 6. Reaction of compound 6 with HCl in MeOH produced 3-methyl ethers of 6-oxoestrone and Δ6-estrone, compounds 12 and 14 (ca. 20% each). Thus, 6-oxosteroids 5 and 6 showed unique C(10)-C(19) bond cleavage reactions with a base or acid.

1,4-Addition reaction with thiols and conformational analysis with PM3 molecular orbital calculations of 19-oxygenated androst-4-ene-3,6,17-triones

Numazawa,Oshibe,Matsuzaki

, p. 423 - 428 (2007/10/02)

Reactions of androst-4-ene-3,6,17-trione (1) and its 19-hydroxy or 19-oxo derivative (2 or 3), suicide substrates of aromatase, with thiols were initially studied. Treatment of 4-ene-3,6-diones 1-3 with benzyl-mercaptan in MeOH at room temperature gave th

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 1091-89-0