109121-41-7

Upstream product

• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 88406-01-3 2,3-O-isopropylidene-1-C-<(1R)-1-methylprop-2-enyl>-D-erythro-glycerol 
• 100-39-0 benzyl bromide 

Downstream Products

• 109066-08-2 5,6-di-O-benzyl-1,2,3-trideoxy-3-methyl-D-gluc-1-enitol 
• 109065-87-4 4,6-di-O-benzyl-1,2,3-trideoxy-3-methyl-D-gluc-1-enitol 
• 109066-07-1 4-O-benzyl-5,6-benzylidene-1,2,3-trideoxy-3-methyl-D-gluc-1-enitol 
• 596095-57-7 (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dien-1-ol 
• 596095-56-6 (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienoic acid methyl ester 
• 596095-58-8 (2E,4E)-(6R,7S)-7-Benzyloxy-7-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,4,6-trimethyl-hepta-2,4-dienal 
• 932718-75-7 benzoic acid (2R,3S,4R)-3-benzyloxy-2-methanesulfonyloxy-4-methyl-hex-5-enyl ester 
• 932718-79-1 ((1S,2S,3R)-2-benzyloxy-1-methoxymethyl-3-methyl-pent-4-ynyloxy)-triisopropylsilane 
• 932718-56-4 ((1S,2S,3R)-2-benzyloxy-1-methoxymethyl-3-methyl-pent-4-enyloxy)-triisopropylsilane 
• 932718-58-6 (2S,3S,4S)-3-benzyloxy-5-methoxy-2-methyl-4-triisopropylsilanyloxy-pentanal 
• 932718-73-5 benzoic acid (2R,3S,4R)-3-benzyloxy-2-hydroxy-4-methyl-hex-5-enyl ester 
• 932718-77-9 (2S,3S,4R)-3-benzyloxy-1-methoxy-4-methyl-hex-5-en-2-ol 
• 932718-54-2 (S)-((1S,2R)-1-benzyloxy-2-methyl-but-3-enyl)-oxirane 
• 596095-52-2 (2S,3S)-3-Benzyloxy-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propionaldehyde 

Relevant academic research and scientific papers

A concise/catalytic approach for the construction of the C14-C28 fragment of eribulin

A simple approach for the synthesis of the C14-C28 fragment of eribulin has been developed by employing a one-pot gold-catalyzed alkynol cyclization/Kishi reduction to construct the 1,5-cis-tetrahydropyran unit and a cross-metathesis/Sharpless asymmetric

Crotylation versus propargylation: Two routes for the synthesis of the C13-C18 fragment of the antibiotic branimycin

The C13-C18 fragment 3 of the novel antibiotic branimycin was prepared along two highly stereocontrolled routes. The first one uses a standard Roush crotylation protocol, whereas the second one proceeds via an allenyl silane propargylation with unexpected stereochemical consequences, which are discussed in detail.

A divergent approach to apoptolidin and FD-891: Asymmetric preparation of a common intermediate

Biologically active Apoptolidin and FD-891 have structural similarity in their macrocyclic cores. Asymmetric preparation of a common intermediate in the total synthesis of these two macrolides is presented. A modified Masuyama Sn-allylation was employed to control the relative stereochemistry in the synthesis of the intermediate.

Stereoselectivity of Electrophile-Promoted Cyclizations of γ-Hydroxyalkenes. An Investigation of Carbohydrate-Derived and Model Substrates

We have investigated cyclization reactions of γ-hydroxyalkenes bearing an alkoxy or alkyl substituent on the allylic carbon.A variety of electrophiles N-bromosuccinimide, N-iodosuccinimide, iodine, mercury(II) acetate, mercury(II) trifluoroacetate, mercu