109164-76-3

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 79074-03-6 2-(benzyloxycarbonylamino)-4-hydroxybutanoic acid 
• 60857-16-1 N-(4-methoxybenzyl)glycine ethyl ester 
• 109392-77-0 2-Benzyloxycarbonylamino-4-(tert-butyl-dimethyl-silanyloxy)-butyric acid 

Downstream Products

• 109164-83-2 (R)-2-[(1R,7R,11S)-8-(4-Methoxy-benzyl)-6,9-dioxo-5,8-diaza-tricyclo[5.2.2.0^1,5]undec-11-yl]-propionic acid ethyl ester 
• 109164-83-2 (S)-2-[(1R,7R,11S)-8-(4-Methoxy-benzyl)-6,9-dioxo-5,8-diaza-tricyclo[5.2.2.0^1,5]undec-11-yl]-propionic acid ethyl ester 
• 109164-85-4 (1R,7R,11S)-11-Isopropenyl-8-(4-methoxy-benzyl)-5,8-diaza-tricyclo[5.2.2.0^1,5]undecane-6,9-dione 
• 109164-85-4 (1R,7R,11R)-11-Isopropenyl-8-(4-methoxy-benzyl)-5,8-diaza-tricyclo[5.2.2.0^1,5]undecane-6,9-dione 
• 109164-79-6 8a-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-(4-methoxy-benzyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione 
• 109164-82-1 (E)-4-[2-(4-Methoxy-benzyl)-1,4-dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-8a-yl]-2-methyl-but-2-enoic acid ethyl ester 
• 109164-78-5 4-(3-Bromo-propyl)-3-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-(4-methoxy-benzyl)-piperazine-2,5-dione 
• 109164-86-5 8a-((E)-4-Hydroxy-3-methyl-but-2-enyl)-2-(4-methoxy-benzyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione 
• 124268-74-2 8a-((E)-4-Chloro-3-methyl-but-2-enyl)-2-(4-methoxy-benzyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione 
• 109164-84-3 (E)-4-[2-(4-Methoxy-benzyl)-1,4-dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-8a-yl]-2-methyl-but-2-enal 
• 109164-81-0 [2-(4-Methoxy-benzyl)-1,4-dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-8a-yl]-acetaldehyde 
• 109164-80-9 8a-(2-Hydroxy-ethyl)-2-(4-methoxy-benzyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione 
• 109392-78-1 3-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-1,4-bis-(4-methoxy-benzyl)-piperazine-2,5-dione 
• 109392-83-8 7,9-bis(p-methoxybenzyl)-3-hydroxy-7,9-diazabicyclo<3.2.2>nonane-6,8-dione 

Relevant academic research and scientific papers

Synthesis of Functionalized Bicyclic Dioxopiperazines via Intramolecular Epoxide Opening

d,l-Homoserine was condensed with N-p-methoxybenzylglycine ethyl ester and alkylated to furnish (2-hydroxyethyl)piperazinedione 8.Oxidation to the correspomding aldehyde and condensation with dimethylsulfoxonium methylide provided the epoxide 10.Enolate f

PROMISING CYCLIZATION REACTIONS TO CONSTRUCT THE RING SYSTEMS OF BREVIANAMIDES A,B

An effective intramolecular Michael cyclization and intramolecular SN2'cyclization is described for constructing the tricyclic framework of the natural mycotoxins brevianamides A,B.