109205-69-8

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 87424-21-3 2'-deoxy-N²-<(9H-fluoren-9-ylmethoxy)carbonyl>guanosine 
• 961-07-9 2'-Deoxyguanosine 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 81144-43-6 5'-O-(p,p'-dimethoxytrityl)-2'-deoxyguanosine 

Relevant academic research and scientific papers

N-FMOC NUCLEOSIDES AND PHOSPHORAMIDITES, AND OLIGONUCLEOTIDE SYNTHESIS

This invention relates to synthesis of novel -N-FMOC protected nucleosides, succinates, phosphoramidites, corresponding solid supports that are suitable for oligo deoxy nucleosides and RNA oligonucleotide synthesis. Our discovery using N- FMOC as nucleosi

The 9-fluorenylmethoxycarbonyl (Fmoc) group and its use in oligonucleotide synthesis

The introduction of the base-labile 9-fluorenylmethoxycarbonyl (Fmoc) group into the exocyclic amino function of 2'-deoxynucleosides and their dimethoxytritylation and phosphitylation is described. The resulting key intermediates were investigated in the