1092075-08-5Relevant academic research and scientific papers
Stereoselective synthesis of enynones via base-catalyzed isomerization of 1,5-disubstituted-2,4-pentadiynyl silyl ethers or their alcohol derivatives
Chen, Jingjin,Fan, Guoqin,Liu, Yuanhong
supporting information; experimental part, p. 4806 - 4810 (2010/12/19)
1,5-Disubstituted-2,4-pentadiynyl silyl ethers undergo smooth desilylative isomerization to afford cis-enynones as major products with moderate stereoselectivities in the presence of a catalytic amount of KOtBu or DBU. While the isomerization reactions of their alcohol derivatives catalyzed by KOH, KOtBu or NaH take place efficiently to produce trans-enynones with high stereoselectivities. These reactions provide convenient and practical routes for the synthesis of enynones with a wide range of substitution groups.
Dialkyltitanium-mediated titanation of conjugated 1,3-butadiynes and its coupling reactions with aldehydes: a facile synthesis of stereodefined enynes and trans-enynols
Chen, Jingjin,Liu, Yuanhong
scheme or table, p. 6655 - 6658 (2009/04/07)
A highly efficient and convenient method for the selective titanation of 1,3-butadiynes using Ti(OiPr)4/nBuLi reagent has been developed. The method provided a facile synthesis of enynes and trans-enynols in a well-stereod
