109208-45-9

Upstream product

• 556-52-5 oxiranyl-methanol 
• 64-04-0 phenethylamine 

Downstream Products

• 344870-16-2 (3-Phenethyl-2-phenyl-oxazolidin-5-yl)-methanol 
• 344601-12-3 Toluene-4-sulfonic acid 3-phenethyl-2-phenyl-oxazolidin-5-ylmethyl ester 
• 85613-54-3 1-Phenethylamino-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)-phenoxy]-propan-2-ol 

Relevant academic research and scientific papers

Enhanced cellular uptake by "pharmaceutically oriented devices" of new simplified analogs of Linezolid with antimicrobial activity

The aim of the present study was to enhance cellular uptake of simplified analogs of Linezolid by their incorporation into suitable delivery devices in order to improve the antimicrobial activity of these novel synthesized oxazolidin-2-one derivatives. Th

β1-Selective adrenoceptor antagonists: Examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class

A series of 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazoles is described. The compounds were investigated in vitro for β-adrenoceptor antagonism, and several examples were found to be selective for the β1-adrenoceptor. The structure-activity relationship exhibited by this series of compounds is discussed. (S)-2-[p-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-hydroxypropoxy]phenyl] -4-(2-thienyl)imidazole [(S)-13] was over 100 times more selective than atenolol for the β1-adrenergic receptor and has been selected for in-depth studies.