1092099-63-2

Upstream product

• 1092099-62-1 (2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine methyl ester 

Downstream Products

• 1092099-64-3 {(2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-2,2,2-trichloroethoxycarbonyl-amino]pyrrolidin-2-yl}-[4-(2-methoxy-phenyl)-piperazin-1-yl]methanone 

Relevant academic research and scientific papers

PROLINAMIDE DERIVATIVES AS NK3 ANTAGONISTS

The present invention relates to a compound of formula I wherein R2 R3, R4, R5, X, n, and o are as defined herein and to a pharmaceutically acceptable acid addition salt thereof which are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).