1092399-18-2Relevant academic research and scientific papers
Initial catalyst-substrate association step in enyne metathesis catalyzed by Grubbs ruthenium complex probed by time-dependent fluorescence quenching
Sohn, Jeong-Hun,Kyung, Hwan Kim,Lee, Hee-Yoon,Zae, Sung No,Ihee, Hyotcherl
, p. 16506 - 16507 (2008)
This communication introduces an FRET-based simple and efficient method for monitoring kinetics and thermodynamics of organic reactions and describes its application to studies on the initial catalyst-substrate association step in the enyne metathesis catalyzed by a Grubbs Ru complex to probe the reaction initiation on the alkyne versus the alkene. The kinetic and thermodynamic parameters of alkene and alkyne with the first generation Grubbs Ru complex, determined by the time-dependent fluorescence quenching of the dye-conjugated substrate by the Ru catalyst, strongly support the dominance of the reaction initiation on alkene over alkyne in the reaction both kinetically and thermodynamically. Copyright
Correlation between functionality preference of ru carbenes and exo / endo product selectivity for clarifying the mechanism of ring-closing enyne metathesis
Lee, Ok Suk,Kim, Kyung Hwan,Kim, Jinwoo,Kwon, Kuktae,Ok, Taedong,Ihee, Hyotcherl,Lee, Hee-Yoon,Sohn, Jeong-Hun
, p. 8242 - 8249 (2013/09/24)
Functionality preferences of metathesis Ru carbenes to various alkenes and alkynes with electronic and steric diversity were determined by using time-dependent fluorescence quenching. The functionality preferences depend not only on the properties of mult
