109240-69-9Relevant academic research and scientific papers
ASYMMETRIC SYNTHESIS OF (R)-(+)- AND (S)-(-)-2,2,4-TRIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE OF HIGH ENANTIOMERIC PURITY
Tanner, David,Somfai, Peter
, p. 5985 - 5990 (2007/10/02)
The title compounds, 1 and 1', are readily available in four steps from 2-benzyloxymethyl-2-propen-1-ol, the key step being Sharpless asymmetric epoxidation to give the chiral epoxides 5 or 5'.The total chemical yield of 1 or 1' is 50percent, the final pr
