109240-65-5Relevant articles and documents
ASYMMETRIC SYNTHESIS OF (R)-(+)- AND (S)-(-)-2,2,4-TRIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE OF HIGH ENANTIOMERIC PURITY
Tanner, David,Somfai, Peter
, p. 5985 - 5990 (1986)
The title compounds, 1 and 1', are readily available in four steps from 2-benzyloxymethyl-2-propen-1-ol, the key step being Sharpless asymmetric epoxidation to give the chiral epoxides 5 or 5'.The total chemical yield of 1 or 1' is 50percent, the final pr
Chiral primary amine catalyzed asymmetric epoxidation of α-substituted acroleins
Li, Jiuyuan,Fu, Niankai,Zhang, Long,Zhou, Pengxin,Luo, Sanzhong,Cheng, Jin-Pei
experimental part, p. 6840 - 6849 (2011/03/19)
1,1-Disubstituted terminal alkenes remain challenging substrates in asymmetric epoxidation reactions. In this study, chiral primary amines are shown to catalyze the asymmetric epoxidation of α-substituted acroleins, a versatile type of 1,1-disubstituted t
