109245-01-4

Upstream product

• 30414-53-0 methyl propanoyl acetate 
• 62-53-3 aniline 
• 22377-44-2 methyl 2,3-pentadienoate 
• 1193-02-8 4-aminotiophenol 

Downstream Products

• 1268524-07-7 C₁₇H₂₃NO₅ 
• 135015-84-8 ZD 8731 
• 135015-56-4 methyl-4'-<<(2-ethylquinolin-4-yl)oxy>methyl>biphenyl-2-carboxylate 
• 135015-57-5 4'-[(2-ethylquinolin-4-yloxy)methyl]biphenyl-2-carboxylic acid 
• 1268522-81-1 6-ethyl-N-[1-(hydroxyacetyl)piperidin-4-yl]-1-methyl-4-oxo-5-phenyl-3-(2,2,2-trifluoroethoxy)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxamide 
• 1268523-49-4 ethyl 6-ethyl-1-methyl-3-(1-methylethoxy)-4-oxo-5-phenyl-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate 
• 1268523-47-2 ethyl 3-ethoxy-6-ethyl-1-methyl-4-oxo-5-phenyl-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate 
• 1268523-37-0 6-ethyl-1-methyl-4-oxo-5-phenyl-3-(2,2,2-trifluoroethoxy)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid 
• 1268523-36-9 ethyl 6-ethyl-1-methyl-4-oxo-5-phenyl-3-(2,2,2-trifluoroethoxy)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate 
• 1268523-35-8 ethyl 6-ethyl-3-hydroxy-1-methyl-4-oxo-5-phenyl-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate 
• 1268523-34-7 ethyl 4-chloro-6-ethyl-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxylate 
• 1268523-33-6 ethyl 6-ethyl-4-hydroxy-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxylate 
• 1268523-32-5 ethyl 6-ethyl-4-hydroxy-2-oxo-1-phenyl-1,2,5,6-tetrahydropyridine-3-carboxylate 
• 1268523-31-4 methyl 3-(phenylamino)pentanoate 

Relevant academic research and scientific papers

IMIDAZO [1,5-A] PYRAZINE DERIVATIVES AS PI3Kdelta INHIBITORS

Disclosed is a compound of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of treating PI3Kδ related disorders or diseases by using the c

A general and efficient method for synthesis of enaminones and enamino esters catalyzed by NbCl5 under solvent-free conditions

A general and simple procedure was developed for the synthesis of β-enaminones and β-enamino esters by reacting 1,3-dicarbonyl compounds with amines in the presence of catalytic amounts of niobium pentachloride. The reaction proceeds smoothly at room temperature under solvent-free conditions and leads to chemo- and regioselective formation of enamine derivatives in high to excellent yields.

FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF

The present invention provides a fused heterocycle derivative having a strong Smo inhibitory activity, and use thereof. Specially, the present invention relates to a compound represented by the formula wherein each symbol is as defined in the specificatio

New nonpeptide angiotensin II receptor antagonists. 2. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4- (biphenylylmethoxy)quinoline derivatives

A novel series of nonpeptidic angiotensin II (AII) receptor antagonists is reported, derived from linkage of the biphenylcarboxylic acid or biphenylyltetrazole moiety found in previously described antagonists via a methyleneoxy chain to the 4-position of

Regioselectivity of Addition of Thiols and Amines to Conjugated Allenic Ketones and Esters

Regioselectivity of nucleophilic addition to conjugated allenic ketones depends strongly on the nucleophile: anionic nucleophiles, e.g., triethylamine salts of benzenethiols, gave the β-substituted β,γ-unsaturated ketones with high selectivity.In contrast