135015-84-8

Basic information

• Product Name: Quinoline,2-ethyl-4-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methoxy]-, hydrochloride(1:1)
• Synonyms: Quinoline,2-ethyl-4-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methoxy]-,monohydrochloride (9CI); ZD 8731
• CAS NO: 135015-84-8
• Molecular Formula: C25H21 N5 O . Cl H
• Molecular Weight: 443.936
• Mol File: 135015-84-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Quinoline,2-ethyl-4-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methoxy]-, hydrochloride(1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline,2-ethyl-4-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methoxy]-, hydrochloride(1:1)(135015-84-8)
• EPA Substance Registry System: Quinoline,2-ethyl-4-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methoxy]-, hydrochloride(1:1)(135015-84-8)

Safety Data

• Hazardous Substances Data: 135015-84-8(Hazardous Substances Data)

Upstream product

• 143805-52-1 2-ethyl-4-[(2'-(1-(4-nitrophenyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methoxy]quinoline 
• 108-10-1 4-methyl-2-pentanone 
• 143805-61-2 2-ethyl-4-[(2'-(1-(pyridin-4-yl)-1H-tetrazol-5-yl)biphenyl-4-yl)methoxy]quinoline 
• 107-03-9 1-thiopropane 
• 62-53-3 aniline 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 
• 109245-01-4 ethyl 3-(phenylamino) pent-2-enoate 
• 109072-25-5 2-ethyl-4(1H)-quinolone 
• 30414-53-0 methyl propanoyl acetate 

Relevant articles and documents

QUINOLINE DERIVATIVES AND USE THEREOF AS ANGIOTENSIN II ANTAGONISTS

The invention concerns pharmaceutically useful novel compounds of the formula I, in which R 1, R 2, R 3, R 4, R 5, Ra, A, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment. STR1

Heterocyclic boron compounds as intermediates for angiotensin II antagonists

The invention concerns novel boron compounds of the formula IV, in which Q, Y 1, G 1 and G 2 have the various meanings defined herein, and their acid and base addition salts. The said compounds are useful in the manufacture of certain quinoline, pyridine and imidazole derivatives which have angiotensin II inhibitory activity. The invention also provides novel processes for the production of the quinoline, pyridine and imidazole derivatives. STR1