1092458-78-0Relevant articles and documents
First chemoenzymatic synthesis of organoselenium amines and amides
Andrade, Leandro H.,Silva, Alexandre V.
, p. 1175 - 1181 (2008/09/21)
A series of organoselenium amines have been synthesized and submitted to the enzymatic kinetic resolution by acetylation mediated by CAL-B (Novozym 435) to give the corresponding chiral amides in an enantiomerically pure form. After evaluating the appropriate lipase, solvent, temperature, and lipase/substrate ratio in the kinetic resolution, the chiral organoselenium amides were obtained with enantiomeric excess of up to 99%.
