1092565-35-9Relevant articles and documents
Identification of novel thiazolo[5,4-b]pyridine derivatives as potent phosphoinositide 3-kinase inhibitors
Dong, Yi,Lin, Songwen,Tian, Hua,Xia, Liang,Xu, Heng,Zhang, Jingbo,Zhang, Kehui,Zhang, Yan
, (2020/10/18)
A series of novel 2-pyridyl, 4-morpholinyl substituted thiazolo[5,4-b]pyridine analogues have been designed and synthesized in this paper. These thiazolo[5,4-b]pyridines were efficiently prepared in seven steps from commercially available substances in mo
NAPHTHYRIDINE, DERIVATIVES AS P13 KINASE INHIBITORS
-
Page/Page column 76, (2009/01/24)
Invented is a method of inhibiting the activity/function of PB kinases using naphthyridine derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of naphthyridine derivatives.