1400667-74-4

Basic information

• Product Name: N-(5-(4-(tetrahydro-2H-pyran-4-yloxy)pyrido[3,2-d]pyrimidin-6-yl)pyridin-3-yl)-2,4-difluorobenzenesulfonamide
• Synonyms: N-(5-(4-(tetrahydro-2H-pyran-4-yloxy)pyrido[3,2-d]pyrimidin-6-yl)pyridin-3-yl)-2,4-difluorobenzenesulfonamide
• CAS NO: 1400667-74-4
• Molecular Weight: 499.498
• Mol File: 1400667-74-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(5-(4-(tetrahydro-2H-pyran-4-yloxy)pyrido[3,2-d]pyrimidin-6-yl)pyridin-3-yl)-2,4-difluorobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-(4-(tetrahydro-2H-pyran-4-yloxy)pyrido[3,2-d]pyrimidin-6-yl)pyridin-3-yl)-2,4-difluorobenzenesulfonamide(1400667-74-4)
• EPA Substance Registry System: N-(5-(4-(tetrahydro-2H-pyran-4-yloxy)pyrido[3,2-d]pyrimidin-6-yl)pyridin-3-yl)-2,4-difluorobenzenesulfonamide(1400667-74-4)

Safety Data

• Hazardous Substances Data: 1400667-74-4(Hazardous Substances Data)

Upstream product

• 93683-65-9 6-chloro-3-nitropicolinonitrile 
• 13535-01-8 3-amino-5-bromopyridine 
• 16013-85-7 2,6-dicholoro-3-nitropyridine 
• 13918-92-8 2,4-difluorobenzene-1-sulfonyl chloride 
• 175358-02-8 4,6-dichloropyrido<3,2-d>pyrimidine 
• 171178-33-9 6-chloropyrido[3,2-d]pyrimidin-4(1H)-one 
• 175358-01-7 3-amino-6-chloro-pyridine-2-carboxylic acid amide 
• 1083326-23-1 N-(5-bromo-3-pyridinyl)-2,4-difluorobenzenesulfonamide 
• 1092565-35-9 2,4-difluoro-N-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)benzenesulfonamide 
• 1400668-02-1 6-chloro-4-(tetrahydro-2H-pyran-4-yloxy)pyrido[3,2-d]pyrimidine 

Relevant articles and documents

NOVEL PYRIDOPYRIMIDINE DERIVATIVES AND USE THEREOF

The invention provides novel substituted pyridopyrimidines represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of the phosphoinositide 3′ OH kinase family (PI3K) for the treatment of inflammatory diseases, cancer, cardiovascular diseases, allergy, asthma and autoimmune disorders.