109274-06-8

Basic information

• Product Name: (3R,5S)-3-Benzylamino-6-{2-[3-(4-fluoro-phenoxy)-propyl]-4,6-dimethyl-phenoxy}-5-hydroxy-hexanoic acid benzylamide
• Synonyms: (3R,5S)-3-Benzylamino-6-{2-[3-(4-fluoro-phenoxy)-propyl]-4,6-dimethyl-phenoxy}-5-hydroxy-hexanoic acid benzylamide
• CAS NO: 109274-06-8
• Molecular Weight: 598.758
• Mol File: 109274-06-8.mol

Chemical Properties

• CAS DataBase Reference: (3R,5S)-3-Benzylamino-6-{2-[3-(4-fluoro-phenoxy)-propyl]-4,6-dimethyl-phenoxy}-5-hydroxy-hexanoic acid benzylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5S)-3-Benzylamino-6-{2-[3-(4-fluoro-phenoxy)-propyl]-4,6-dimethyl-phenoxy}-5-hydroxy-hexanoic acid benzylamide(109274-06-8)
• EPA Substance Registry System: (3R,5S)-3-Benzylamino-6-{2-[3-(4-fluoro-phenoxy)-propyl]-4,6-dimethyl-phenoxy}-5-hydroxy-hexanoic acid benzylamide(109274-06-8)

Safety Data

• Hazardous Substances Data: 109274-06-8(Hazardous Substances Data)

Upstream product

• 109273-99-6 (S)-6-{2-[3-(4-Fluoro-phenoxy)-propyl]-4,6-dimethyl-phenoxymethyl}-5,6-dihydro-pyran-2-one 
• 100-46-9 benzylamine 
• 108002-35-3 (4R,6S)-6-{2-[3-(4-Fluoro-phenoxy)-propyl]-4,6-dimethyl-phenoxymethyl}-4-hydroxy-tetrahydro-pyran-2-one 
• 108025-19-0 (4R,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-6-{2-[3-(4-fluoro-phenoxy)-propyl]-4,6-dimethyl-phenoxymethyl}-tetrahydro-pyran-2-one 

Relevant articles and documents

CONVENIENT TWO-STEP STEREOSPECIFIC HYDROXY-SUBSTITUTION WITH RETENTION IN β-HYDROXY-δ-LACTONES. 4(R)-HETEROSUBSTITUTED MEVINOLIN AND -ANALOGS

Michael additions of mercaptanes and amines to optically pure 6-alkyl-5,6-dihydro-2H-pyran-2-ones of the mevinolin type -5 and the aromatic analog -7 are stereospecific to give 4(R)-substituted mevinolin analogs.