109274-62-6

Basic information

• Product Name: [1-(6-fluoro-4-methylquinolin-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid
• CAS NO: 109274-62-6
• Molecular Formula: C₁₇H₁₆FN₃O₂
• Molecular Weight: 313.3262
• Mol File: 109274-62-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 530.5°C at 760 mmHg
• Flash Point: 274.6°C
• Density: 1.32g/cm³
• Vapor Pressure: 4.4E-12mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: [1-(6-fluoro-4-methylquinolin-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(6-fluoro-4-methylquinolin-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid(109274-62-6)
• EPA Substance Registry System: [1-(6-fluoro-4-methylquinolin-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]acetic acid(109274-62-6)

Safety Data

• Hazardous Substances Data: 109274-62-6(Hazardous Substances Data)

Upstream product

• 108099-80-5 6-fluoro-2-hydrazino-4-methylquinoline 
• 18529-12-9 2-chloro-6-fluoro-4-methylquinoline 
• 108936-76-1 [1-(6-Fluoro-4-methyl-quinolin-2-yl)-3,5-dimethyl-1H-pyrazol-4-yl]-acetic acid ethyl ester 

Relevant articles and documents

Synthesis of Some 2-(3',5'-Dimethylpyrazol-1'-yl)-4-methyl-6-substituted-quinolines and Their 4'-Substituted Analogues

The reaction of 2-hydrazinoquinolines (2) with pentane-2,4-dione yields pyrazoles (1) instead of the reported diazepines (3).The structural assignment is based on a rigorous spectral analysis of the product and on unambiguous synthesis.Several pyrazolylquinolines (1, 6 and 7) bearing a variety of substituents were synthesized and evaluated for their antiinflammatory and antimalarial activities.