1092961-07-3 Usage
Description
4-Fluoro-1-methylindazole is a chemical compound belonging to the class of indazoles, which are bicyclic aromatic heterocycles. It is characterized by the presence of a fluoro group and a methyl group attached to the indazole ring structure. 4-Fluoro-1-methylindazole has potential applications in pharmaceutical research, particularly in the development of new drugs and therapeutic agents. Its specific properties and biological activities are of interest to researchers in the field of medicinal chemistry, as it may exhibit pharmacological effects that could be relevant for the treatment of various diseases. Ongoing research is exploring its potential as a drug candidate.
Uses
Used in Pharmaceutical Research:
4-Fluoro-1-methylindazole is used as a research compound for the development of new drugs and therapeutic agents. Its unique structure and properties make it a promising candidate for the discovery of novel pharmacological effects that could be relevant for the treatment of various diseases.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-Fluoro-1-methylindazole is used as a starting material or a building block for the synthesis of more complex molecules with potential therapeutic applications. Its specific properties and biological activities are being studied to understand its potential as a drug candidate and to design new molecules with improved pharmacological profiles.
Used in Drug Discovery:
4-Fluoro-1-methylindazole is used as a lead compound in drug discovery programs. Researchers are investigating its potential to modulate biological targets and pathways implicated in various diseases. 4-Fluoro-1-methylindazole's structure and functional groups can be further optimized to enhance its potency, selectivity, and pharmacokinetic properties, leading to the development of more effective therapeutic agents.
Used in Chemical Synthesis:
4-Fluoro-1-methylindazole serves as a versatile intermediate in the synthesis of a wide range of chemical compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity make it a valuable building block for the preparation of novel molecules with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1092961-07-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,2,9,6 and 1 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1092961-07:
(9*1)+(8*0)+(7*9)+(6*2)+(5*9)+(4*6)+(3*1)+(2*0)+(1*7)=163
163 % 10 = 3
So 1092961-07-3 is a valid CAS Registry Number.
1092961-07-3Relevant articles and documents
Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands
Taylor, Nicholas J.,Emer, Enrico,Preshlock, Sean,Schedler, Michael,Tredwell, Matthew,Verhoog, Stefan,Mercier, Joel,Genicot, Christophe,Gouverneur, Véronique
supporting information, p. 8267 - 8276 (2017/06/27)
Molecules labeled with fluorine-18 (18F) are used in positron emission tomography to visualize, characterize and measure biological processes in the body. Despite recent advances in the incorporation of 18F onto arenes, the development of general and efficient approaches to label radioligands necessary for drug discovery programs remains a significant task. This full account describes a derisking approach toward the radiosynthesis of heterocyclic positron emission tomography (PET) radioligands using the copper-mediated 18F-fluorination of aryl boron reagents with 18F-fluoride as a model reaction. This approach is based on a study examining how the presence of heterocycles commonly used in drug development affects the efficiency of 18F-fluorination for a representative aryl boron reagent, and on the labeling of more than 50 (hetero)aryl boronic esters. This set of data allows for the application of this derisking strategy to the successful radiosynthesis of seven structurally complex pharmaceutically relevant heterocycle-containing molecules.
A method for the regioselective synthesis of 1-alkyl-1H-indazoles
Liu, Han-Jun,Hung, Shiang-Fu,Chen, Chuan-Lin,Lin, Mei-Huey
, p. 3907 - 3912 (2013/06/27)
A method for the regioselective synthesis of 3-unsubstituted 1-alkyl-1H-indazoles, starting with 2-halobenzonitriles and N-alkylhydrazines, is described. The two-step reaction pathway proceeds through the intermediacy of 1-alkyl-3-amino-1H-indazoles follo
