162502-44-5

Basic information

• Product Name: 3-Amino-4-fluoro-1-methylindazole
• Synonyms: 3-Amino-4-fluoro-1-methylindazole;4-Fluoro-1-methyl-1H-indazol-3-ylamine
• CAS NO: 162502-44-5
• Molecular Formula: C8H8FN3
• Molecular Weight: 165.17
• Mol File: 162502-44-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 325.2°C at 760 mmHg
• Flash Point: 150.5°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 0.000234mmHg at 25°C
• Refractive Index: 1.643
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 3-Amino-4-fluoro-1-methylindazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-4-fluoro-1-methylindazole(162502-44-5)
• EPA Substance Registry System: 3-Amino-4-fluoro-1-methylindazole(162502-44-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 162502-44-5(Hazardous Substances Data)

Usage

General Description

3-Amino-4-fluoro-1-methylindazole is a chemical compound with the molecular formula C9H8N3F. It is a derivative of indazole, a heterocyclic aromatic organic compound. This chemical is known for its potential use in pharmaceutical research and drug development due to its unique structure and properties. It is also commonly used as a building block in the synthesis of other compounds, particularly in medicinal chemistry. 3-Amino-4-fluoro-1-methylindazole has been studied for its potential biological activity and is of interest to researchers in the field of medicinal chemistry and drug discovery.

InChI:InChI=1/C8H8FN3/c1-12-6-4-2-3-5(9)7(6)8(10)11-12/h2-4H,1H3,(H2,10,11)

Upstream product

• 1897-52-5 2,6 difluorobenzonitrile 
• 60-34-4 methylhydrazine 

Downstream Products

• 1092961-07-3 4-fluoro-1-methyl-1H-indazole 

Relevant articles and documents

A method for the regioselective synthesis of 1-alkyl-1H-indazoles

A method for the regioselective synthesis of 3-unsubstituted 1-alkyl-1H-indazoles, starting with 2-halobenzonitriles and N-alkylhydrazines, is described. The two-step reaction pathway proceeds through the intermediacy of 1-alkyl-3-amino-1H-indazoles follo

Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides

Substituted ring annulated 5-alkoxy-N-aryl-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide compounds, such as N-(2,6-dichlorophenyl)-5-methoxycyclopenteno[d]-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide, were prepared by condensation of an appropriate 2-chloro-sulfonyl-5-alkoxy[1,2,4]triazolo[1,5-c]pyrimidine compound, such as 2-chlorosulfonyl-5-methoxycyclopenteno[d][1,2,4]triazolo[1,5-c]pyrimidine, with a substituted arylamine compound, such as 2,6-dichloroaniline, and found to possess herbicidal utility.

N-indazolyl[1,2,4]triazolo[1,5-C]pyrimidine-2-sulfonamide herbicides

Substituted N-indazolyl[1,2,4]triazolo[1,5]-c-pyrimidine-2-sulfonamide compounds, such as N-(4-fluoro-1-methyl-3-indazolyl)-5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide, were prepared by condensation of a 2-chlorosulfonyl[1,2,4]triazolo[1,5-c]pyrimidine compound, such as 2-chlorosulfonyl-5-ethoxy-7-fluoro[1,2,4]triazolo[1,5-c]pyrimidine, with a substituted 3-aminoindazole compound, such as 3-amino-4-fluoro-1-methylindazole, and found to possess herbicidal utility.