1093087-06-9

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 3-amino-5-fluoro-4-methylbenzoate serves as an intermediate in the production of pharmaceuticals, contributing to the synthesis of various medicinal compounds due to its unique chemical structure and reactivity.
Used in Agrochemical Industry:
In the agrochemical sector, Methyl 3-amino-5-fluoro-4-methylbenzoate is employed as an intermediate for the synthesis of pesticides and other agrochemical products, leveraging its chemical properties to enhance the effectiveness of these compounds.
Used in Fine Chemicals Production:
Methyl 3-amino-5-fluoro-4-methylbenzoate is also utilized in the creation of other fine chemicals, where its specific molecular structure is key to achieving desired chemical reactions and end products.

Upstream product

• 1095005-99-4 2-chloro-5-fluoro-4-methyl-3-nitro-benzoic acid methyl ester 
• 103877-61-8 2-chloro-5-fluoro-4-methyl-benzoic acid 
• 103877-62-9 2-chloro-5-fluoro-4-methyl-3-nitro-benzoic acid 
• 1095005-98-3 2-chloro-5-fluoro-4-methyl-benzoic acid methyl ester 
• 201849-17-4 1-bromo-2-chloro-5-fluoro-4-methylbenzene 

Downstream Products

• 1095006-00-0 3-[(cyanomethyl)amino]-5-fluoro-4-methyl-benzoic acid, methyl ester 
• 1095006-01-1 3-(3,5-dibromo-2-oxo-2H-pyrazin-1-yl)-5-fluoro-4-methyl-benzoic acid, methyl ester 
• 1095006-03-3 3-[5-bromo-2-oxo-3-[[1-[2-(phenylmethoxy)phenyl]cyclopropyl]amino]-1(2H)-pyrazinyl]-5-fluoro-4-methyl-benzoic acid, methyl ester 
• 1095006-05-5 3-fluoro-5-[3-[[1-(2-hydroxyphenyl)cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-4-methyl-benzoic acid, methyl ester 
• 1095006-07-7 N-cyclopropyl-3-fluoro-5-[3-[[1-(2-hydroxyphenyl)cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-4-methyl-benzamide 
• 1095006-08-8 3-[3-[[1-[2-(2-chloroethoxy)phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-N-cyclopropyl-5-fluoro-4-methyl-benzamide 
• 1095004-78-6 N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxopyrazin-1-yl]benzamide 
• 1232287-20-5 methyl 3-[3-[1-[2-[2-[(benzyloxycarbonyl)methylamino]ethoxy]phenyl]cyclopropylamino]-5-bromo-2-oxo-1(2H)-pyrazinyl]-5-fluoro-4-methylbenzoate 
• 1232287-22-7 benzyl[2-[2-[1-[[6-bromo-4-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-3-oxo-3,4-dihydro-2-pyrazinyl]amino]cyclopropyl]phenoxy]ethyl]methylcarbamate 
• 1095005-88-1 N-cyclopropyl-3-fluoro-5-[3-[[1-(2-hydroxyphenyl)-1-methylethyl]amino]-2-oxo-1(2H)-pyrazinyl]-4-methyl-benzamide 
• 1095005-89-2 3-[3-[[1-[2-(2-chloroethoxy)phenyl]-1-methylethyl]amino]-2-oxo-1(2H)-pyrazinyl]-N-cyclopropyl-5-fluoro-4-methyl-benzamide 
• 1095006-02-2 3-[5-bromo-3-[[1-methyl-1-[2-(phenylmethoxy)phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]-5-fluoro-4-methyl-benzoic acid, methyl ester 
• 1095004-69-5 N-cyclopropyl-3-[3-[[1-[2-[2-(ethylamino)ethoxy]phenyl]-1-methylethyl]amino]-2-oxo-1(2H)-pyrazinyl]-5-fluoro-4-methyl-benzamide 
• 1095005-87-0 3-[5-bromo-3-[[1-methyl-1-[2-(phenylmethoxy)phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]-N-cyclopropyl-5-fluoro-4-methyl-benzamide 

Relevant academic research and scientific papers

Pharmaceutical Product Comprising a P38 Kinase Inhibitor and a Second Active Ingredient

The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is N-Cyclopropyl-3-fluoro-4-methyl-5[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-benzamide or a salt thereo

NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS

Heteroaryloxy-substituted benzoic acid amides of general formula I wherein the groups R1 to R7 as well as X and Y are defined according to claim 1, including the tautomers, the stereoisomers, the mixtures and the salts thereof. The compounds according to the invention are suitable for the treatment of respiratory complaints, particularly COPD and asthma.

PYRAZINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF LUNG DISEASES

The present invention relates to py razinone derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6 and R7 are as herein defined; processes for their preparation, pharmaceutical compositions containing them and their use in therapy.