1093191-90-2

Upstream product

• 76-83-5 trityl chloride 
• 596-43-0 bromo-triphenyl-methane 
• 728877-98-3 (2S,3S)-methyl 3-hydroxy-2-(tritylamino)butanoate 
• 728877-99-4 3-(R)-azido-2-(S)-(tritylamino)butyric acid methyl ester 

Downstream Products

• 1093191-93-5 (2S,3R)-3-Boc-amino-2-tritylaminobutyric acid methyl ester 
• 1093191-91-3 (2S,3R)-3-Fmoc-amino-2-tritylaminobutyric acid methyl ester 
• 1093191-92-4 (2S,3R)-2-amino-3-Fmoc-aminobutyric acid methyl ester hydrochloride 

Relevant academic research and scientific papers

UREA DERIVATIVES AS ANTIBACTERIAL AGENTS

This invention relates to compounds of the Formula (I):or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which is useful for the treatment of diseases or conditions mediated by LpxC.

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.