1093281-33-4Relevant articles and documents
Identification of C5-NH2 Modified Oseltamivir Derivatives as Novel Influenza Neuraminidase Inhibitors with Highly Improved Antiviral Activities and Favorable Druggability
Bertagnin, Chiara,Du, Ruikun,Guizzo, Laura,Hou, Lingxin,Huang, Bing,Jia, Ruifang,Ju, Han,Kang, Dongwei,Kong, Xiujie,Li, Ping,Liu, Xinyong,Loregian, Arianna,Ma, Xiuli,Murugan, N. Arul,Poongavanam, Vasanthanathan,Zhan, Peng,Zhang, Ying
, p. 17992 - 18009 (2021/11/18)
Our previous efforts have proved that modifications targeting the 150-cavity of influenza neuraminidase can achieve more potent and more selective inhibitors. In this work, four subseries of C5-NH2 modified oseltamivir derivatives were designed
BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS
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Page/Page column 54, (2011/06/11)
This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of benzimidazoles in the treatment of cancer.