109339-64-2Relevant academic research and scientific papers
Nickel and Nucleophilic Cobalt-Catalyzed Trideuteriomethylation of Aryl Halides Using Trideuteriomethyl p-Toluenesulfonate
Komeyama, Kimihiro,Yamahata, Yuta,Osaka, Itaru
supporting information, p. 4375 - 4378 (2018/07/29)
Herein, a novel approach for the trideuteriomethylation of aryl halides using nickel and nucleophilic cobalt catalysts and the readily available trideuteriomethyl p-toluenesulfonate (CD3OTs) is described. This method provides access to a wide r
Development of a Rhodium(II)-Catalyzed Chemoselective C(sp3)-H Oxygenation
Lin, Yun,Zhu, Lei,Lan, Yu,Rao, Yu
supporting information, p. 14937 - 14942 (2015/10/19)
We report the first example of RhII-catalyzed chemoselective double C(sp3)-H oxygenation, which can directly transform various toluene derivatives into highly valuable aromatic aldehydes with great chemoselectivity and practicality. The critical combination of catalyst Rh(OAc)2, oxidant Selectfluor, and solvents of TFA/TFAA promises the successful delivery of the oxidation with satisfactory yields. A possible mechanism involving a unique carbene-Rh complex is proposed, and has been supported by both experiments and theoretical calculations.
