1093390-01-2Relevant academic research and scientific papers
Towards novel S-DABOC inhibitors: Synthesis, biological investigation, and molecular modeling studies
Radi, Marco,Angeli, Lucilla,Franchi, Luigi,Contemori, Lorenzo,Maga, Giovanni,Samuele, Alberta,Zanoli, Samantha,Armand-Ugon, Mercedes,Gonzalez, Emmanuel,Llano, Anuska,Este, Jose A.,Botta, Maurizio
supporting information; experimental part, p. 5777 - 5780 (2009/08/15)
A small family of S-DABO cytosine analogs (S-DABOCs) has been synthesized and biologically evaluated as HIV-1 inhibitor both on wild type (wt) and drug-resistant mutants leading to the identification of an interesting compound (5d). Molecular modeling studies have been finally performed in order to rationalize the results.
