1093656-53-1Relevant articles and documents
Synthesis of dipyrrins bearing chirality adjacent to the conjugated skeleton - Electron-poor pyrroles exhibit dramatically reduced nucleophilicity
Beshara, Cory S.,Pearce, Beth M.,Thompson, Alison
, p. 951 - 957 (2008/12/23)
With the aim of furthering our investigations into the asymmetric complexation of dipyrrinato ligands, a dipyrrin bearing a stereogenic centre directly adjacent to the conjugated skeleton was synthesized. The electronwithdrawing nature of the chiral 4-(2,2,2-trifluoro-1-hydroxyethyl)- substituent significantly reduced the nucleophilicity of corresponding pyrroles, such that 2,2′-symmetrically substituted bis(dipyrrin)s bearing this motif were inaccessible. Furthermore, solutions of mononuclear dipyrrinato complexes were found to be less stable to acid-catalyzed decomplexation than the corresponding dinuclear complexes.
