1093846-33-3Relevant academic research and scientific papers
Highly enantioselective organocatalytic conjugate addition of nitromethane to benzylidene acetones
Sznt, Gbor,Grün, Alajos,Kdas, Istvn,Bombicz, Petra
, p. 1120 - 1126 (2008)
Six active 4-aryl-5-nitro-pentan-2-ones were synthesized enantioselectively from the corresponding 5-aryl-butenones by asymmetric Michael addition of nitromethane using an imidazolidine-type enantioselective organocatalyst. The ee ratio of the products we
Effective asymmetric Michael addition of acetone to nitroalkenes promoted by chiral proline amide-thiourea bifunctional catalysts
Wang, Qiao-Wei,Peng, Lin,Fu, Ji-Ya,Huang, Qing-Chun,Wang, Li-Xin,Xua, Xiaoying
experimental part, p. 340 - 351 (2010/08/04)
A series of secondary amine-thiourea catalysts 1a-1d derived from L-proline and chiral diamine were prepared and successfully applied to the Michael addition of acetone to trans-nitroalkenes in excellent yields (up to 99%) and enantioselectivities (44-91%
