1093959-80-8

Basic information

• Product Name: pentafluorophenyl 2-phenyl-3-methylbutanoate
• Synonyms: pentafluorophenyl 2-phenyl-3-methylbutanoate
• CAS NO: 1093959-80-8
• Molecular Weight: 344.281
• Mol File: 1093959-80-8.mol

Chemical Properties

• CAS DataBase Reference: pentafluorophenyl 2-phenyl-3-methylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: pentafluorophenyl 2-phenyl-3-methylbutanoate(1093959-80-8)
• EPA Substance Registry System: pentafluorophenyl 2-phenyl-3-methylbutanoate(1093959-80-8)

Safety Data

• Hazardous Substances Data: 1093959-80-8(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 3508-94-9 3-methyl-2-phenylbutyric acid 

Downstream Products

• 1169704-44-2 C₂₀H₂₁NO₂S 
• 1308658-87-8 C₁₇H₂₁NO₅ 
• 1308658-88-9 C₁₇H₂₁NO₅ 
• 1308658-99-2 C₂₀H₂₁NO₃ 
• 1308658-97-0 C₂₀H₂₁NO₃ 
• 1308658-79-8 C₁₇H₂₃NO₃ 
• 1308658-77-6 C₁₆H₂₁NO₃ 
• 1308658-76-5 C₁₆H₂₁NO₃ 

Relevant articles and documents

Parallel kinetic resolution of active esters using a quasi-enantiomeric combination of (R)-4-phenyl-oxazolidin-2-one and (S)-4,5,5-triphenyl-oxazolidin-2-one

The parallel kinetic resolution of a series of racemic pentafluorophenyl 2-(4-aryl/phenyl)-propionates and -butanoates using a quasi-enantiomeric combination of (R)-4-phenyl-oxazolidin-2-one and (S)-4,5,5-triphenyl-oxazolidin-2-one is discussed. The levels of diastereoselectivity were excellent (86-98% de) leading to separable quasi-enantiomeric oxazolidin-2-one adducts in good yield. This methodology was used to resolve 2-phenyl propionic acid.

Efficient parallel resolution of pentafluorophenyl active esters using quasi-enantiomeric combinations of oxazolidin-2-ones

The parallel resolution of racemic pentafluorophenyl 2-aryl/ phenylpropanoates and butanoates using an equimolar combination of quasi-enantiomeric Evans oxazolidin-2-ones is discussed. The levels of diastereoselectivity were excellent (>90% de) leading to separable quasi-enantiomeric oxazolidin-2-ones in good yield. This methodology was used to resolve a series of structurally related 2-aryl/phenylpropanoic and butanoic acids.