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Epsilon-dinitrophenyllysine is the L-stereoisomer of N6-(2,4-dinitrophenyl)lysine, a lysine derivative with a 2,4-dinitrophenyl substituent at the N6-position. It is a chemical compound that has been studied for its potential applications in various fields.

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  • 1094-76-4 Structure
  • Basic information

    1. Product Name: epsilon-dinitrophenyllysine
    2. Synonyms: epsilon-dinitrophenyllysine
    3. CAS NO:1094-76-4
    4. Molecular Formula: C12H16N4O6
    5. Molecular Weight: 312.2786
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1094-76-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 571.6°Cat760mmHg
    3. Flash Point: 299.5°C
    4. Appearance: /
    5. Density: 1.46g/cm3
    6. Vapor Pressure: 6.6E-14mmHg at 25°C
    7. Refractive Index: 1.641
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: epsilon-dinitrophenyllysine(CAS DataBase Reference)
    11. NIST Chemistry Reference: epsilon-dinitrophenyllysine(1094-76-4)
    12. EPA Substance Registry System: epsilon-dinitrophenyllysine(1094-76-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1094-76-4(Hazardous Substances Data)

1094-76-4 Usage

Uses

Used in Research Applications:
Epsilon-dinitrophenyllysine is used as a research tool for studying protein structure and function. Its unique chemical properties allow it to interact with proteins and other biomolecules, providing insights into their mechanisms of action.
Used in Analytical Chemistry:
Epsilon-dinitrophenyllysine is used as an analytical reagent in various assays and tests. Its ability to bind to specific molecules makes it a valuable component in detecting and quantifying the presence of certain substances.
Used in Pharmaceutical Development:
Epsilon-dinitrophenyllysine has potential applications in the development of new pharmaceuticals. Its interaction with proteins and other biomolecules may lead to the discovery of novel therapeutic agents for various diseases and conditions.
Used in Environmental Monitoring:
Epsilon-dinitrophenyllysine can be used in environmental monitoring to detect the presence of pollutants or contaminants. Its binding properties make it a useful tool for identifying and quantifying harmful substances in the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 1094-76-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,9 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1094-76:
(6*1)+(5*0)+(4*9)+(3*4)+(2*7)+(1*6)=74
74 % 10 = 4
So 1094-76-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N4O6/c13-9(12(17)18)3-1-2-6-14-10-5-4-8(15(19)20)7-11(10)16(21)22/h4-5,7,9,14H,1-3,6,13H2,(H,17,18)/t9-/m0/s1

1094-76-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N6-(2,4-dinitrophenyl)-L-lysine

1.2 Other means of identification

Product number -
Other names N(6)-(2,4-dinitrophenyl)-L-lysine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1094-76-4 SDS

1094-76-4Downstream Products

1094-76-4Relevant articles and documents

A peptide-based fluorescent probe images ERAAP activity in cells and in high throughput assays

Zhang, Jingtuo,Yang, Soo Jung,Gonzalez, Federico,Yang, Jiaying,Zhang, Yumiao,He, Maomao,Shastri, Nilabh,Murthy, Niren

, p. 7215 - 7218 (2018)

ERAAP is an intracellular amino-peptidase that plays a central role in determining the repertoire of peptides displayed by cells by MHC class I molecules, and dysfunctions in ERAAP are linked to a variety of diseases. There is therefore great interest in developing probes that can image ERAAP in cells. In this report we present a fluorescent probe, termed Ep, that can image ERAAP activity in live cells. Ep is composed of a 10 amino acid ERAAP substrate that has a donor quencher pair conjugated to it, composed of BODIPY and dinitro-toluene. Ep undergoes a 20-fold increase in fluorescence after ERAAP cleavage, and was able to image ERAAP activity in cell culture via fluorescence microscopy. In addition, we used Ep to develop a high throughput screen for ERAAP inhibitors, and screened an electrophile library containing 1460 compounds. From this Ep based screen we identified aromatic alkyne-ketone as a lead fragment that can irreversibly inhibit ERAAP activity. We anticipate numerous applications of Ep given its unique ability to image ERAAP within cells.

CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS

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Page/Page column 31-32, (2011/11/30)

The invention relates to solid supports useful in medical applications that provide controlled release of drugs, such as peptides, nucleic acids and small molecules. The drugs are covalently coupled to the solid support through a linkage that releases the drug or a prodrug through controlled beta elimination.

CONTROLLED RELEASE FROM MACROMOLECULAR CONJUGATES

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Page/Page column 24-25, (2011/11/30)

The invention relates to conjugates of macromolecular carriers and drugs comprising linkers that release the drug or a prodrug through rate-controlled beta-elimination, and methods of making and using the conjugates.

HIGHLY AFFINE COSMETIC AGENT

-

Page 25; 26, (2008/06/13)

The invention relates to a cosmetic agent which is made essentially of a peptide linker and at least one cosmetic active ingredient which is covalently connected thereto.

Synthesis and application of unprotected cyclic peptides as building blocks for peptide dendrimers

Zhang, Lianshan,Tam, James P.

, p. 2363 - 2370 (2007/10/03)

We describe an efficient regiospecific method for cyclization of unprotected peptide segments based on intramolecular transthioesterification of unprotected cysteinyl peptide thioesters under the control of ring-chain tautomeric equilibrium in aqueous buf

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