109423-85-0Relevant academic research and scientific papers
Rapid and efficient synthesis of (R)-aryloxypropionic acid esters under microwave irradiation
Ochal, Zbigniew,Durka, Krzysztof,Banach, Lukasz
experimental part, p. 3209 - 3213 (2010/12/24)
A series of (R)-(+)-ethyl aryloxypropionates (4a-4p) have been synthesized by the reaction of substituted phenols with ethyl (S)-(-)-tosyloxy lactate under the conditions of microwave irradiation and without solvents. The reaction conditions have been optimized. A good method for the preparation of (R)-(+)-ethyl aryloxypropionate was developed, with good yields, high enantiomer excess, short reaction times, easy workup, and simple procedure. Copyright Taylor & Francis Group, LLC.
PROCESS FOR PREPARING (R)-ARYLOXYPROPIONIC ACID ESTER DERIVATIVES
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Page 10, (2008/06/13)
The present invention relates to a method for preparing optically active (R)-aryloxypropionic acid ester derivatives, and more particularly to a method for preparing (R)- aryloxypropionic acid ester derivatives with high optical purity and good yield at low cost from phenol derivatives with various substituted functional groups and (S)-alkyl O-arylsulfonyl lactates.
