1094322-44-7Relevant articles and documents
Discovery of selective nonpeptidergic neuropeptide FF2 receptor agonists
Gaubert, Gilles,Bertozzi, Fabio,Kelly, Nicholas M.,Pawlas, Jan,Scully, Audra L.,Nash, Norman R.,Gardell, Luis R.,Lameh, Jelveh,Olsson, Roger
supporting information; experimental part, p. 6511 - 6514 (2010/03/26)
We report the discovery and initial characterization of a novel class of selective NPFF2 agonists. HTS screening using R-SAT, a whole cell based functional assay, identified a class of aryliminoguanidines as NPFF1 and NPFF2 ligands. Subsequent optimizatio
Bright, color-tunable fluorescent dyes in the Vis/NIR region: Establishment of new "tailor-made" multicolor fluorophores based on borondipyrromethene
Umezawa, Keitaro,Matsui, Akihiro,Nakamura, Yuki,Citterio, Daniel,Suzuki, Koji
experimental part, p. 1096 - 1106 (2009/09/29)
A new series of high-performance fluorophores named Keio Fluors (KFL), which are based on borondipyrromethene (BODIPY), are reported. The KFL dyes cover a wide spectral range from the yellow (547 nm) to the near-infrared (NIR, 738 nm) region, and their emission wavelength could be easily and subtly controlled based on simple molecular modifications only, without losing their optical properties. This "tailor-made" synthetic strategy for tuning the emission wavelength enabled the creation of fourteen KFL dyes with well-controlled emission colors (yellow, orange, red, far-red, and NIR). Moreover, these KFL dyes also retain their excellent optical properties, such as spectral bands sharper than quantum dots, high extinction coefficients (140000-316000 M-1 cm-1), and high quantum yields (0.56-0.98), without any critical solvent polarity dependent decrease of their brightness. These advantageous characteristics make the KFL dyes potentially useful as new candidates of fluorescent standard dyes to substitute or to complement existing long-wavelength fluorescent dyes, such as cyanines, oxazines, rhodamines, or other BODIPY dyes.
