1094627-41-4 Usage
General Description
2-Amino-2-(2-methylphenyl)ethan-1-ol, also known as α-methylbenzeneethanamine, is an organic compound with the chemical formula C9H13NO. It is a secondary amine and an alcohol, containing both an amino group and a hydroxyl group. 2-AMino-2-(2-Methylphenyl)ethan-1-ol is commonly used in pharmaceutical and chemical research as a building block to synthesize various drugs and molecules. It also has potential applications in the field of organic synthesis and as a chiral auxiliary in asymmetric synthesis. It is important to handle this compound with care, as it may pose potential health risks if not properly handled or used in a controlled manner.
Check Digit Verification of cas no
The CAS Registry Mumber 1094627-41-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,4,6,2 and 7 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1094627-41:
(9*1)+(8*0)+(7*9)+(6*4)+(5*6)+(4*2)+(3*7)+(2*4)+(1*1)=164
164 % 10 = 4
So 1094627-41-4 is a valid CAS Registry Number.
1094627-41-4Relevant articles and documents
Directed β C-H Amination of Alcohols via Radical Relay Chaperones
Wappes, Ethan A.,Nakafuku, Kohki M.,Nagib, David A.
, p. 10204 - 10207 (2017/08/10)
A radical-mediated strategy for β C-H amination of alcohols has been developed. This approach employs a radical relay chaperone, which serves as a traceless director that facilitates selective C-H functionalization via 1,5-hydrogen atom transfer (HAT) and enables net incorporation of ammonia at the β carbon of alcohols. The chaperones presented herein enable direct access to imidate radicals, allowing their first use for H atom abstraction. A streamlined protocol enables rapid conversion of alcohols to their β-amino analogs (via in situ conversion of alcohols to imidates, directed C-H amination, and hydrolysis to NH2). Mechanistic experiments indicate HAT is rate-limiting, whereas intramolecular amination is product- and stereo-determining.
